His scoring streak at Atlético continued and, once again, Falcao was important for his team in the game that faced Real Betis at the Benito Villamarín Stadium, where Atlético began winning and with 5 minutes to go Betis came back from behind to put the mattress club at a 2-1 disadvantage, Falcao scored with a header in injury time the important goal that gave them the long-suffering tie. El Tigre scored the discount goal for Atlético Madrid, which at the time meant the tie for the team. Bilbao, came out victorious with a 2-1 in Madrid, and also with a double from the Colombian. It should be noted that such an event caused the Colombian to sign the best first round of an Atlético footballer since 1999, with 14 goals in 19 games. With these two goals, Falcao also became the Atlético player who scored the most goals in the UEFA Europa League, and the top scorer in the competition, with 12 goals in 15 games.

Four days after playing in the Madrid derby, García was once again the starter in the matchday 34 of the Liga BBVA 11-12, between Rayo Vallecano and Atlético Madrid, in which he was fundamental for his team by scoring the only goal of Atlético Madrid, a goal that meant the final 0-1, which gave them an important victory that until then, brought them closer to the qualifying positions for the UEFA Champions League and Europa League. For the Spanish league, he played on March 11 against Granada CF, and actively participated by scoring the second goal of the match that ended 2-0 at the Vicente Calderón. On December 21, he played his first and only match for the 2011-12 Copa del Rey, in his club's defeat against Albacete with a score of 0-1, at the Vicente Calderón. Roberto Soldado, Denis Suárez, Samu Castillejo, Samuel García Sánchez, Cédric Bakambu, Mariano Barbosa, Alphonse Aréola (on loan from PSG), Daniele Bonera, Leo Baptistao (on loan from Atlético) and Adrián López Álvarez (on loan from Porto) are signed ). Mariano Salvador Maella decorated the room's vault with the fresco The Four Seasons of the Year, executed in 1769. A series of consoles, from the mid-18th century, and a set of tapestries on the Trojan War close the room.

This match against FC Barcelona was played at the Vicente Calderón, on February 25, and ended with a 2-1 defeat, against the rojiblanco team. The 1-0 victory for Atlético in the second leg played at the Vicente Calderón Stadium marked the end of a 15-year streak without victories in official matches against their classic rival playing at home. In the last match of the group stage of the Europa League against the Stade Rennais at the Vicente Calderón, which ended in a 3-1 victory, Falcao scored the first goal for his team from a penalty kick. Falcao played his first game of the year 2012 with a match tied without goals, on January 7 at La Rosaleda against Málaga CF in the Liga BBVA, in which Diego Simeone's debut as coach of the colchonero was highlighted. ↑ "The Royal Society exacerbates the crisis of Seville.".

On October 5, Alexis starts and scores two goals and an assist in the 4-1 victory over Real Valladolid, being praised by various media as the figure of the match. On February 16, the UEFA Europa League resumed, with the round of 32 of the championship, a phase in which Atlético Madrid had to face SS Lazio from Italy. Atlético played in the 2011-12 UEFA Europa League final. In this way, on May 9, 2012, the mattress team faced Athletic Club at the Arena Națională in Romania. On February 23, the second leg of the round of 32 of the UEFA Europa League was played against Lazio, and it resulted in 1-0, in favor of the colchonero, without Radamel's presence on the scoreboard. ↑ In the history of the confrontations the result of 5-0, known as a "little hand", has a special meaning. The club's board of directors announces at the end of the season the disappearance of the baseball section for economic reasons, just after winning the fourth title in its history in the national league.